Penbrook is a borough in Dauphin County, Pennsylvania. It is located in the central part of the state, with Philadelphia to the east about a two hour drive away. According to the United States Census Bureau, as of 2000, Penbrook has a population of over 3,000 people. The borough has a total area of 0.5 square miles, all of it land. The racial demographics of Penbrook was 77.33% White, 15.24% African American, 0.23% Native American, 1.61% Asian, 1.87% from other races, and 3.71% from two or more races. Hispanic or Latino of any race were 4.60% of the population. Penbrook is home to over 1,300 households. The median income for a household in the borough is $35,341, and the median income for a family is $44,375. Dauphin County is bordered by seven counties in central and southeastern Pennsylvania. The county has a population of over 250,000 people. It has a land area of 558 square miles, of which 32 square miles of it is water. Dauphin County has 16 boroughs, 23 townships and 10 unincorporated places. The county seat is Harrisburg.

Dauphin County has plenty of parkland and beautiful natural landscapes. It is home to two Pennsylvania State Parks of Boyd Big Tree Preserve and Joseph E. Ibberson Conservation Area. Additionally, the Susquehanna River runs along the county's western border. Dauphin County is home to multiple colleges and universities such as Central Pennsylvania's Community College, The Harrisburg University of Science and Technology and Temple University Harrisburg Campus. The county is served by 12 school districts.